Metabolic response of perfused livers to various oxygenation conditions

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Metabolic response of perfused livers to various oxygenation conditions.

Isolated liver perfusion systems have been used to characterize intrinsic metabolic changes in liver as a result of various perturbations, including systemic injury, hepatotoxin exposure, and warm ischemia. Most of these studies were done using hyperoxic conditions (95% O(2)) but without the use of oxygen carriers in the perfusate. Prior literature data do not clearly establish the impact of ox...

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ژورنال

عنوان ژورنال: Biotechnology and Bioengineering

سال: 2011

ISSN: 0006-3592

DOI: 10.1002/bit.23261